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Batch queries can be done using pipe "|" as a separator between search terms.
Note: Direct classification on the basis of the prior probability alone is a misuse of the Bayesian integrated evaluation model, therefore the dynamic range of the prior probability (Prior P) has been truncated to a minimum of 0.10 and a maximum of 0.90 so that additional sources of information are required to reach posterior probabilities that alter clinical management of patients with variants.
| General information |
| Gene name |
In silico MLH1 priors |
| Gene symbol |
MLH1 |
| Chromosome Location |
3p22.3 |
| Database location |
Tavtigian lab - Huntsman Cancer Institute |
| Curator |
Bryony Thompson |
| Database reference for citations |
Thompson et al., 2013 |
| PubMed references |
View all (unique) PubMed references in the MLH1_priors database |
| Date of creation |
January 09, 2014 |
| Last update |
March 10, 2014 |
| Version |
MLH1 140310 |
| Add sequence variant |
Submit a sequence variant |
| First time submitters |
Register here |
| Genomic refseq ID |
NG_007109.2 |
| Transcript refseq ID |
NM_000249.3 |
| Total number of unique DNA variants reported |
4981 |
| Total number of individuals with variant(s) |
4981 |
| Total number of variants reported |
4981 |
| Subscribe to updates of this gene |
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| Search the database |
| By type of variant |
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| Simple search |
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| Advanced search |
Query the database by selecting a combination of variables |
| Based on patient origin |
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| Copyright & disclaimer |
The contents of this LOVD database are the intellectual property of the respective curator(s). Any unauthorised use, copying, storage or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2024. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.
We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising out of any inaccuracies or omissions. Individuals, organisations and companies which use this database do so on the understanding that no liability whatsoever either direct or indirect shall rest upon the curator(s) or any of their employees or agents for the effects of any product, process or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided. |
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