Batch queries can be done using pipe "|" as a separator between search terms. Note: Direct classification on the basis of the prior probability alone is a misuse of the Bayesian integrated evaluation model, therefore the dynamic range of the prior probability (Prior P) has been truncated to a minimum of 0.10 and a maximum of 0.90 so that additional sources of information are required to reach posterior probabilities that alter clinical management of patients with variants.
LOVD MLH1_priors homepage

General information
Gene name In silico MLH1 priors
Gene symbol MLH1
Chromosome Location 3p22.3
Database location Tavtigian lab - Huntsman Cancer Institute
Curator Bryony Thompson
Database reference for citations Thompson et al., 2013
PubMed references View all (unique) PubMed references in the MLH1_priors database
Date of creation January 09, 2014
Last update March 10, 2014
Version MLH1 140310
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Genomic refseq ID NG_007109.2
Transcript refseq ID NM_000249.3
Total number of unique DNA variants reported 4981
Total number of individuals with variant(s) 4981
Total number of variants reported 4981
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Graphical displays and utilities
Summary tables Summary of all sequence variants in the MLH1_priors database, sorted by type of variant (with graphical displays and statistics)
UCSC Genome Browser Show variants in the UCSC Genome Browser (compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Sequence variant tables
Unique sequence variants Listing of all unique sequence variants in the MLH1_priors database, without patient data
Complete sequence variant listing Listing of all sequence variants in the MLH1_priors database
Variants with no known pathogenicity Listing of all MLH1 variants reported to have no noticeable phenotypic effect (note: excluding variants of unknown effect)
Download table Download the full sequence variant table of the MLH1_priors database in tab-delimited text format.

Search the database
By type of variant View all sequence variants of a certain type
Simple search Query the database by selecting the most important variables (exon number, type of variant, disease phenotype)
Advanced search Query the database by selecting a combination of variables
Based on patient origin View all variants based on your patient origin search terms

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