Batch queries can be done using pipe "|" as a separator between search terms. Note: Direct classification on the basis of the prior probability alone is a misuse of the Bayesian integrated evaluation model, therefore the dynamic range of the prior probability (Prior P) has been truncated to a minimum of 0.10 and a maximum of 0.90 so that additional sources of information are required to reach posterior probabilities that alter clinical management of patients with variants.
LOVD MSH6_priors homepage

General information
Gene name In silico MSH6 priors
Gene symbol MSH6
Chromosome Location 2p16
Database location Tavtigian lab - Huntsman Cancer Institute
Curator Bryony Thompson
Database reference for citations Thompson et al., 2013
PubMed references View all (unique) PubMed references in the MSH6_priors database
Date of creation January 09, 2014
Last update February 07, 2014
Version MSH6 140207
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Genomic refseq ID NG_007111.1
Transcript refseq ID NM_000179.2
Total number of unique DNA variants reported 8948
Total number of individuals with variant(s) 8948
Total number of variants reported 8948
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Graphical displays and utilities
Summary tables Summary of all sequence variants in the MSH6_priors database, sorted by type of variant (with graphical displays and statistics)
UCSC Genome Browser Show variants in the UCSC Genome Browser (compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Sequence variant tables
Unique sequence variants Listing of all unique sequence variants in the MSH6_priors database, without patient data
Complete sequence variant listing Listing of all sequence variants in the MSH6_priors database
Variants with no known pathogenicity Listing of all MSH6 variants reported to have no noticeable phenotypic effect (note: excluding variants of unknown effect)
Download table Download the full sequence variant table of the MSH6_priors database in tab-delimited text format.

Search the database
By type of variant View all sequence variants of a certain type
Simple search Query the database by selecting the most important variables (exon number, type of variant, disease phenotype)
Advanced search Query the database by selecting a combination of variables
Based on patient origin View all variants based on your patient origin search terms

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